abstract：:The liver lipogenic enzymes are compared among rats, chickens, frogs and fish. Although the apparent Km values of glucose-6-phosphate dehydrogenase for glucose-6-phosphate are not much different among all the species, those of malic enzyme for malate are much higher in chickens and fish than in rats and frogs. Glucose...

journal_title：Lipids

authors： Iritani N,Ikeda Y,Fukuda H,Katsurada A

更新日期：1984-11-01 00:00:00

abstract：:The effectiveness of different fatty acids as inhibitors of fatty acyl delta 5 desaturation activity in human skin fibroblasts has been investigated. When incubated with 2.25 microM [14C] eicosatrienoate (20:3 omega 6) in otherwise lipid-free medium, these cells rapidly incorporate the radiolabeled fatty acid into cel...

journal_title：Lipids

authors： Rosenthal MD,Doloresco MA

更新日期：1984-11-01 00:00:00

abstract：:In guinea pigs, total plasma cholesterol concentrations increased above the control values after single intravenous injections and after 3 days of continuous subcutaneous administration of neurotensin (NT). A high dose of NT (125 pmol/100 g body weight) induced tachycardia and severe respiratory distress; the lowest d...

journal_title：Lipids

authors： Peric-Golia L,Gardner CF,Wilson DE,Peric-Golia M

更新日期：1984-10-01 00:00:00

abstract：:The triacylglycerols of very low density lipoproteins (VLDL-TG) were analyzed in samples from normal subjects and patients with Frederickson's Type III and Type IV hyperlipoproteinemia. VLDL were obtained by conventional ultracentrifugation, and the triacylglycerols were isolated by thin-layer chromatography (TLC). Re...

journal_title：Lipids

authors： Myher JJ,Kuksis A,Breckenridge WC,Little JA

更新日期：1984-09-01 00:00:00

abstract：:Accurate quantification of the major classes and subfractions of human serum lipoproteins is an important analytical need in the characterization and evaluation of therapy of lipid and lipoprotein abnormalities. For calibrating the analytic ultracentrifuge (AnUC), we routinely use a Beckman calibration wedge cell with...

journal_title：Lipids

authors： Kahlon TS,Adamson GL,Glines LA,Lindgren FT,Laskaris MA,Shore VG

更新日期：1984-07-01 00:00:00

abstract：:The degradation of exogenous radioactively labeled fatty acids by 5-day-old barley shoots was examined. [1-(14)C] Linoleic acid was observed to be degraded 7 times faster than [1-(14)C] oleic acid and 5 times faster than [1-(14)C] palmitic acid. The pathway of degradation was determined by identifying the water-solubl...

journal_title：Lipids

authors： Nabors LA,Morgan MS,Newman DW,Jaworski JG

更新日期：1984-07-01 00:00:00

abstract：:The effect of essential fatty acid (EFA) deficiency on rat-brain myelin proteins was studied. Rats were maintained on a lipid-free diet and compared with control rats fed the same diet supplemented with 3% corn oil. At 17 days of age, each pup was injected with [3H]leucine and rats from each group were killed over a p...

journal_title：Lipids

authors： Miller SL,Klurfeld DM,Loftus B,Kritchevsky D

更新日期：1984-06-01 00:00:00

abstract：:The levels of arachidonic acid and linoleic acid found in the lipid fraction of human milk samples were compared. No correlation was found between the level of precursor linoleate and product arachidonate in 80 samples of colostrum (day 3-5) or 60 samples of mature breast milk. We attempted to test the hypothesis that...

journal_title：Lipids

authors： Gibson RA,Kneebone GM

更新日期：1984-06-01 00:00:00

abstract：:Thermally oxidized rapeseed oils (4 levels of deterioration; used by a manufacturer of fried fish paste in a conventional manner) were fed to rats at a practical level of concentration. Rats were fed a diet ad libitum for 13 weeks that contained 15% of a test oil. The effects of the diet on several biochemical criteri...

journal_title：Lipids

authors： Izaki Y,Yoshikawa S,Uchiyama M

更新日期：1984-05-01 00:00:00

abstract：:Binding antibodies to surface membranes stimulated incorporation of fatty acids (FA) into phospholipids of L cells. Antibodies stimulated at least a 3.4-fold greater incorporation of arachidonic acid into phosphatidylinositol than into any other class of phospholipid when compared on a molar basis (p less than 0.003)....

journal_title：Lipids

authors： Shearer WT,Ulrich RG

更新日期：1984-04-01 00:00:00

abstract：:The levels of long-chain acyl-CoA in the livers of rats given diets containing various amounts of dietary oils were investigated. Increasing the amount of soybean oil in the diet from 5% to 25% (w/w) led to a 40% increase in long-chain acyl-CoA. With partially hydrogenated marine oil, a sigmoidal dose-response curve w...

journal_title：Lipids

authors： Nilsson A,Thomassen MS,Christiansen E

更新日期：1984-03-01 00:00:00

abstract：:Rats were fed semipurified diets containing olive oil or partially hydrogenated corn oil at the 5 or 20% level for ca. 30 days. These fat diets contained the same amount of octadecenoate but differed in the geometry with respect to each fat level. Contents of t-18:1 were 26% and 41% of total fatty acids, respectively....

journal_title：Lipids

authors： Watanabe M,Cho YJ,Ide T,Sugano M

更新日期：1984-02-01 00:00:00

abstract：:Taurolithocholic acid and deoxycholic acid were perfused into isolated prairie dog livers. Taurolithocholic acid was 7 alpha-hydroxylated to form taurochenodeoxycholic acid, whereas deoxycholic acid was conjugated and 7 alpha-hydroxylated to form taurocholic acid. The low concentrations of secondary bile acids observe...

journal_title：Lipids

authors： Cohen BI,Singhal AK,Mongelli J,Rothschild MA,McSherry CK,Mosbach EH

更新日期：1983-12-01 00:00:00

abstract：:Lipoproteins from the plasma of three nonlactating Holstein cows were isolated using either preparative ultracentrifugation or gel filtration chromatography. Lipoprotein classes obtained by ultracentrifugation were very low density plus chylomicra, less than 1.006 g/ml; low density, 1.007-1.039 g/ml; high density1, 1....

journal_title：Lipids

authors： Grummer RR,Davis CL,Hegarty HM

更新日期：1983-11-01 00:00:00

abstract：:Corn oil, peanut oil and randomized peanut oil exhibit different atherogenic potentials; peanut oil being more atherogenic than the other oils. This study was conducted to ascertain if the atherogenicity of these oils was related to their rates of lipolysis. Using both pancreatic lipase and milk lipoprotein lipase (LP...

journal_title：Lipids

authors： Kim HK,Kritchevsky D

更新日期：1983-11-01 00:00:00

abstract：:Choline kinase was located in the cytosolic fractions of the filamentous, pathogenic fungi,Microsporum gypseum andEpidermophyton floccosum. A broad pH optima (6.0-9.0) was observed for theM. gypseum enzyme, but theE. floccosum enzyme was active at pH 8.4 as well as 10.5, the activity being higher at pH 8.4. Enzyme fro...

journal_title：Lipids

authors： Kasinathan C,Govindarajan U,Chopra A,Khuller GK

更新日期：1983-10-01 00:00:00

abstract：:In experiments with 4 different types of cells, we evaluated the cholesterogenic activity by incorporation of 14C-acetic acid into cholesterol and digitonin-precipitable sterols. In every case, the cholesterogenesis appeared considerably faster when expressed as digitonid than when expressed as real cholesterol produc...

journal_title：Lipids

authors： Tabacik C,Aliau S,Crastes de Paulet A

更新日期：1983-09-01 00:00:00

abstract：:In view of the findings that omega 3 fatty acids inhibit the synthesis of prostaglandins (PG) from arachidonic acid (20:4 omega 6) and that among immunologically active cells, the macrophage is a major producer of PG, we undertook a study of the effect of dietary alpha-linolenic acid (18:3 omega 3) on PG synthesis in ...

journal_title：Lipids

authors： Magrum LJ,Johnston PV

更新日期：1983-08-01 00:00:00

abstract：:Because bile contains substantial amounts of cholesterol precursors, e.g., squalene and different methyl sterols, the fate of biliary squalene was studied by incubating isolated jejunal loops of the rat in vivo with bile containing 3H-squalene and 14C-cholesterol. After 90 min, no radioactivity was found in plasma lip...

journal_title：Lipids

authors： Strandberg TE

更新日期：1983-08-01 00:00:00

abstract：:Seventy-two surgically obtained Dupuytren's disease palmar-fat (DDPF) specimens and 18 location-matched specimens from patients not suffering from this disease (controls) were studied for their total lipid composition and de novo lipogenic activity. Incubation of "DDPF" with 1-[14C]acetate in oxygen produced [14C]palm...

journal_title：Lipids

authors： Rabinowitz JL,Ostermann L Jr,Bora FW,Staeffen J

更新日期：1983-05-01 00:00:00

abstract：:A lactoperoxidase/H2O2/halide system caused the initiation of linoleate peroxidation as indicated by diene conjugation. Coupled lipid peroxidation was accelerated by iodide, chloride and bromide ions at pH 4.0 and 6.2. No peroxidation occurred in the presence of H2O2 or lactoperoxidase alone. The rate of linoleate per...

journal_title：Lipids

authors： Kanner J,Kinsella JE

更新日期：1983-03-01 00:00:00

abstract：:Because of the known advantages of coupling high performance liquid chromatography with mass spectrometry (HPLC-MS) in biological fluids, studies on the reversed-phase HPLC-MS system for direct analysis of conjugated bile acids in human bile samples are described. Ten samples of gallbladder bile of apparently healthy ...

journal_title：Lipids

authors： Mingrone G,Greco AV,Boniforti L,Passi S

更新日期：1983-01-01 00:00:00

abstract：:A simple method is described for the preparation of [6,7,7(-2)H3] sterols and steroids. The synthesis starts with a Δ(5)-sterol or steroid and involves preparation of the 6-oxo-3α,5α-cyclosteroid, base exchange in the presence of deuterium oxide to introduce two deuteriums at the C-7 position and sodium borodeuteride ...

journal_title：Lipids

authors： Goad LJ,Breen MA,Rendell NB,Rose ME,Duncan JN,Wade AP

更新日期：1982-12-01 00:00:00

abstract：:The effects of tumor growth on lipid metabolism were investigated by evaluating serum lipids, lipoprotein lipase activity (LPLA), the lipogenic enzymes, urinary catecholamines along with serum insulin and glucagon levels. We injected 1.5 X 10(6) cells of rat mammary tumor, AC33, and killed the rats on the 18th day. Se...

journal_title：Lipids

authors： Lanza-Jacoby S,Miller EE,Rosato FE

更新日期：1982-12-01 00:00:00

abstract：:Various physical fractions of the barley kernel were fed to one-day-old female and male chickens to determine their effect on hepatic beta-hydroxy-beta-methylglutaryl coenzyme A (HMG-CoA) reductase, cholesterol 7 alpha-hydroxylase and the lipogenic enzymes, acetyl-CoA carboxylase (ACX), malic enzyme (ME), citrate-clea...

journal_title：Lipids

authors： Burger WC,Qureshi AA,Prentice N,Elson CE

更新日期：1982-12-01 00:00:00

abstract：:A method for the simultaneous quantitative analysis of prostaglandin E2 (PGE2) and PGE3 is described. The PG were analyzed by selected ion monitoring as the methyl ester-TMS ether derivatives of PGB2 and PGB3, respectively. The internal standard for the quantification of both species was [3,3,4,4-2H4]PGE2. A linear re...

journal_title：Lipids

authors： Ferretti A,Flanagan VP,Roman JM

更新日期：1982-11-01 00:00:00

abstract：:Lipid-enriched diets have been related to a high cancer incidence in experimental animals for many years, and more recently, to assorted defects on the immune response. We investigated the effect of incubating human or murine (C3H/HEJ) lymphocytes with saturated (16:0) and unsaturated (18:1, 18:2, 18:3, 20:4) fatty ac...

journal_title：Lipids

authors： Santiago-Delpín EA,Román-Franco AA,Colón JI

更新日期：1982-10-01 00:00:00

abstract：:Fecal bile acid and neutral sterol patterns were studied in eight healthy adult volunteers who were challenged with Vibrio cholerae classical Ogawa 395 strain in the course of vaccine development studies. Bacterial 7 alpha-dehydroxylation of cholic and chenodeoxycholic acids was not altered during experimentally induc...

journal_title：Lipids

authors： Huang CT,Levine MM,Daoud GS,Nalin DR,Nichols BL

更新日期：1982-09-01 00:00:00

abstract：:The alk-1-enyl group of 1-alk-1(1)-enyl-2-acyl-glycerophospholipids (plasmalogens) rapidly combines with mercuric chloride. At 0 C, there was a 1:1 stoichiometry for Hg binding to the reactive enol group of plasmalogens. Aldehydes were not released, indicating that the alkenyl ether bond was not cleaved. Hg binding to...

journal_title：Lipids

authors： Carey EM

更新日期：1982-09-01 00:00:00

abstract：:Arachidonic acid was reduced by hydrazine to yield isomeric eicosatrienoic acids with other products. Methylcis,cis,cis-5,8,11-eicosatrienoate was isolated from the products by silver ion chromatography and preparative gas liquid chromatography in 8% yield. The structure was confirmed by spectral studies and oxidative...

journal_title：Lipids

authors： Ghosh A,Koley M,Dutta J

更新日期：1982-04-01 00:00:00

abstract：:In order to determine the minimal amount of dietary 9-trans, 12-trans-linoleate which can decrease endoperoxide metabolites synthesized and their precursor in rat platelets, graded amounts (0, 0.1, 0.5, 1.0, 2.5%) of the trans-linoleate were fed to rats with a constant amount of all-cis-linoleate (2.5%) for 12 weeks. ...

journal_title：Lipids

authors： Hwang DH,Chanmugam P,Anding R

更新日期：1982-04-01 00:00:00

abstract：:Bile acid contents were determined for isolated rat hepatocytes. During the course of isolating the hepatocytes, perfusion of rat liver with buffer containing 2% albumin eluted a significant amount of bile acids. The elution was proportional to the volume of the buffer and attributable to albumin in the buffer. The is...

journal_title：Lipids

authors： Hashimoto S,Uchida K,Hirata M

更新日期：1982-03-01 00:00:00

abstract：:Studies are reported on the effects of dietary trans fatty acids on the 6- and 9-acyl desaturase activities in the liver microsomes of rats fed essential fatty acid (EFA)-deficient and non-EFA-deficient diets. In experiment I, weanling male rats were fed a semisynthetic diet with either 10% safflower oil (SAF) or 10% ...

journal_title：Lipids

authors： De Schrijver R,Privett OS

更新日期：1982-01-01 00:00:00

abstract：:In this paper, evidence is presented on the capacity of Ehrlich ascites cells to synthesize in vitro monounsaturated fatty acids from radioactive palmitate. Localization of the double bond was determined by ozonolysis and subsequent reduction of the ozonides to aldesters followed by gas liquid chromatography. These re...

journal_title：Lipids

authors： Mercuri O,De Tomás ME,de Antueno RJ

更新日期：1981-12-01 00:00:00

abstract：:Changes in a number of morphological and biochemical parameters were observed in genetically obese Zucker rats and in lean controls between 3 and 58 weeks of age. By 3 weeks, the genetically obese rats had higher proportional (wt/100 g body wt) and absolute amounts of adipose tissue, hyperlipemia affecting all the lip...

journal_title：Lipids

authors： Bach A,Schirardin H,Bauer M,Schaeffer A,Weryha A

更新日期：1981-11-01 00:00:00

abstract：:Chlorpromazine (CPZ), a major tranquilizer, was found to be a potent inhibitor of lecithin:cholesterol acyltransferase (LCAT, EC 2.3.1.43) in the plasma of normal man, rat, rabbit and dog in vitro. The inhibitory effect of CPZ reached 35-50% at 0.5 mM depending on species; dog plasma LCAT appeared to be somewhat more ...

journal_title：Lipids

authors： Bell FP,Hubert EV

更新日期：1981-11-01 00:00:00

abstract：:The accumulation of (1-palmitoyl)lysophosphatidylcholine, lysolecithin, in gallbladder bile was observed during the first week of cholesterol-induced experimental cholelithiasis using the prairie dog model for cholesterol gallstone formation. Gallbladder fluid transport function decreased as bile lysolecithin concentr...

journal_title：Lipids

authors： Rutledge FA 2nd,Hickman DM,Dunn JJ,Frey CF,Matson RS

更新日期：1981-10-01 00:00:00

abstract：:Incorporation of [14C] from acetoacetate, D(-)- and L(+)-3-hydroxybutyrate, glucose, glutamine, acetate and palmitate in cellular lipids were studied in cultures in human diploid fibroblasts (HDF). The results showed that acetoacetate was 2-10 times more effective as a lipogenic precursor than was either D- or L-3-hyd...

journal_title：Lipids

authors： Reed WD,Zielke HR,Baab PJ,Ozand PT

更新日期：1981-09-01 00:00:00

abstract：:Cholesterol and cholesteryl esters were separated according to their carbon number and number of double bonds by high performance reversed-phase chromatography (HPRC) using acetonitrile/chloroform/methanol (1:1:1, v/v) as a mobile phase. It was found that within the same equivalent carbon number (ECN) category, choles...

journal_title：Lipids

authors： Perkins EG,Hendren DJ,Bauer JE,El-Hamdy AH

更新日期：1981-08-01 00:00:00

abstract：:Differences in the positional incorporation of 9-trans[1-(14)C] octadecenoic (elaidic) and 9-trans,12-trans[1-(14)C] octadecadienoic (linoelaidic) acids in fetal lecithin of rats were demonstrated. On the 20th day of gestation, a 14C-labeled albumin complex of elaidic or linoelaidic acid was injected into the jugular ...

journal_title：Lipids

authors： Moore CE,Dhopeshwarkar GA

更新日期：1981-07-01 00:00:00